Postdoctoral Positions
Rare diseases affect more people than Cancer and AIDS combined. There is a tremendous unmet medical need to treat these debilitating diseases. The new tools of molecular therapy, gene and epigenomic editing, can be used to treat these disorders, but the current Wall Street-based development paradigm that creates $2,000,000 treatments is unlikely to provide these treatments to the families devastated by these disorders.
We believe an academic Center for Interventional Genetics can help. Come, and let's try to do things differently.
We are seeking postdocs to lead projects investigating the use of genetic and epigenetic editing in the treatment of neurologic disease, such as Angelman Syndrome, SYNGAP1, and ADNP deficiency. The postdoc will construct and evaluate the on-target and off-target activities and gene expression changes of genetic and epigenetic editing tools in cells and animal models. The applicant must have a Ph.D. and experience with CRISPR as well as molecular genetic analyses (DNA cloning, RTqPCR, Western, ChIP-PCR, transfection, cell cloning). Preferred qualifications include expertise in epi/genomic analyses (ChIP-seq, RNA-seq, 4C, single cell), in-vivo delivery methods (AAV, LNP), and tissue analyses (microscopy, immunohistochemistry).
We welcome applications from enthusiastic scientists whose race, gender, ethnicity, orientation, and culture could bring diversity to our program.
Apply
Applicants should submit a curriculum vita that includes a list of publications and description of research experience, along with contact information for three referees to: djsegal@ucdavis.edu.